for assistance call: 1-888-673-3444
New MUMC Website!
The MU Metagenomics Center recently launched a new website – please visit us at:
http://mumc.missouri.edu
April 06, 2015
The MU Metagenomics Center recently launched a new website – please visit us at:
http://mumc.missouri.edu
Watch the video!
Microbiota Characterization
The gut microbiota (GM) is now recognized as a key factor in health and disease. Differences in the composition of the gut microbiota of research animals may contribute to altered phenotypes or poor reproducibility of animal-based studies. Culture-independent techniques such as next-generation sequencing (NGS) allow in-depth characterization of the gut microbiota. The MMRRC now offers a full line of NGS-related services including fecal DNA extraction, 16S rDNA gene sequencing, and informatics analysis to researchers using mouse models. For more information, please see here or contact mmrrc@missouri.edu.
Please visit
MU METAGENOMICS CENTER (MUMC)
April 02, 2015
Please visit
MU METAGENOMICS CENTER (MUMC)
Journal of the Missouri State Medical Association
June 01, 2013
SCIENCE OF MEDICINE
One Medicine: Collaborative Research on Human & Animal Disease for the Betterment of Both
Craig L. Franklin, DVM, PhD .......... 195
A Brief History of Animal Modeling
Aaron C. Ericsson, DVM, PhD, Marcus J. Crim, DVM & Craig L. Franklin, DVM, PhD .......... 201
New York Times Article Misleads on the Value of Mouse Models
Catherine E. Hagan, DVM, PhD .......... 206
The Mighty Mouse: The Impact of Rodents on Advances in Biomedical Research
Elizabeth C. Bryda, PhD .......... 207
The Laboratory Animal Veterinarian: More than just a Mouse Doctor
Cynthia G. Alvarado, DVM & Lonny M. Dixon, DVM .......... 223
Publications
- Pathogenicity of Helicobacter ganmani in Mice Susceptible and Resistant to Infection with H. hepaticus. Alvarado CG, Kocsis AG, Hart ML, Crim MJ, Myles MH, Franklin CL. Comp Med. 2015;65(1):15-22. PMID: 25730753 [PubMed - in process].
- Effects of vendor and genetic background on the composition of the fecal microbiota of inbred mice. Ericsson AC, Davis JW, Spollen W, Bivens N, Givan S, Hagan CE, McIntosh M, Franklin CL. PLoS ONE. 2015 Feb 12; 10(2): e0116704. doi: 10.1371/journal.pone.0116704. PMCID: PMC4326421.
- The utility of Apc-mutant rats in modeling human colon cancer. Amy A. Irving, Kazuto Yoshimi, Marcia L. Hart, Taybor Parker, Linda Clipson, Madeline R. Ford, Takashi Kuramoto, William F. Dove, James M. Amos-Landgraf. Dis Model Mech. 2014 November; 7(11): 1215–1225. Published online 2014 October 2. doi: 10.1242/dmm.016980. PMCID: PMC4213726.
- The effect of omeprazole on the development of experimental autoimmune encephalomyelitis in C57BL/6J and SJL/J mice. Sands SA, Tsau S, Yankee TM, Parker BL, Ericsson AC, LeVine SM. BMC Res Notes. 2014 Sep 4;7:605. doi: 10.1186/1756-0500-7-605. PMCID: PMC4167283.
- Engraftment of human iPS cells and allogeneic porcine cells into pigs with inactivated RAG2 and accompanying severe combined immunodeficiency. Kiho Lee, Deug-Nam Kwon, Toshihiko Ezashi, Yun-Jung Choi, Chankyu Park, Aaron C. Ericsson, Alana N. Brown, Melissa S. Samuel, Kwang-Wook Park, Eric M. Walters, Dae Young Kim, Jae-Hwan Kim, Craig L. Franklin, Clifton N. Murphy, R. Michael Roberts, Randall S. Prather, Jin-Hoi Kim. Proc Natl Acad Sci U S A. 2014 May 20; 111(20): 7260–7265. Published online 2014 May 5. doi: 10.1073/pnas.1406376111. PMCID: PMC4034252.
- Segmented filamentous bacteria: commensal microbes with potential effects on research. Ericsson AC, Hagan CE, Davis DJ, Franklin CL. Comp Med. 2014 Apr;64(2):90-8. Review. PMCID: PMC3997285.
- A Simple, Quantitative Method Using Alginate Gel to Determine Rat Colonic Tumor Volume In Vivo. Amy A Irving, Lindsay B Young, Jennifer K Pleiman, Michael J Konrath, Blake Marzella, Michael Nonte, Justin Cacciatore, Madeline R Ford, Linda Clipson, James M Amos-Landgraf, William F Dove. Comp Med. 2014 April; 64(2): 128–134. Published online 2014 April. PMCID: PMC3997291.
- APOE3, but Not APOE4, Bone Marrow Transplantation Mitigates Behavioral and Pathological Changes in a Mouse Model of Alzheimer Disease. Yue Yang, Eiron Cudaback, Nikolas L. Jorstad, Jake F. Hemingway, Catherine E. Hagan, Erica J. Melief, Xianwu Li, Tom Yoo, Shawn B. Khademi, Kathleen S. Montine, Thomas J. Montine, C. Dirk Keene. Am J Pathol. 2013 September; 183(3): 905–917. doi: 10.1016/j.ajpath.2013.05.009. PMCID: PMC3763765.
- A Brief History of Animal Modeling. Aaron C. Ericsson, Marcus J. Crim, Craig L. Franklin. Mo Med. 2013 May-Jun; 110(3): 201–205. PMCID: PMC3979591.
- The Mighty Mouse: The Impact of Rodents on Advances in Biomedical Research. Elizabeth C. Bryda. Mo Med. 2013 May-Jun; 110(3): 207–211. PMCID: PMC3987984.
- Development of a PCR Assay for the Detection of Spironucleus muris. Glenn A Jackson, Robert S Livingston, Lela K Riley, Beth A Livingston, Craig L Franklin. J Am Assoc Lab Anim Sci. 2013 March; 52(2): 165–170. Published online 2013 March. PMCID: PMC3624784.
- Conditional deletion of calcium-modulating cyclophilin ligand causes deafness in mice. Bryda EC, Johnson NT, Ohlemiller KK, Besch-Williford CL, Moore E, Bram RJ. Mamm Genome. 2012 Apr;23(3-4):270-6.
- Theriogenology. Foreword. Agca Y. Theriogenology. 2012 Nov;78(8):1639-40. doi: 10.1016/j.theriogenology.2012.08.013. Epub 2012 Sep 13.
- Genome Resource Banking of Biomedically Important Laboratory Animals. Yuksel Agca. Theriogenology. 2012 November; 78(8): 1653–1665. Published online 2012 September 13. doi: 10.1016/j.theriogenology.2012.08.012. PMCID: PMC3939794.