The University of Missouri Mutant Mouse Resource & Research Center is one of four regional centers comprising the MMRRC (http://www.mmrrc.org/). The overall goal of the MMRRC is to provide a center for accepting and distributing high quality, well characterized mutant mice. To this end, the MMRRC will select and import mouse strains important to the biomedical research community; rederive mice to a pathogen-free status; cryopreserve gametes and/or embryos; perform genotyping and infectious disease monitoring to assure the highest quality of mice available, and distribute live mice, cryopreserved germplasm or tissues to investigators.
The gut microbiota (GM) is now recognized as a key factor in health and disease. Differences in the composition of the gut microbiota of research animals may contribute to altered phenotypes or poor reproducibility of animal-based studies. Culture-independent techniques such as next-generation sequencing (NGS) allow in-depth characterization of the gut microbiota. The MMRRC now offers a full line of NGS-related services including fecal DNA extraction, 16S rDNA gene sequencing, and informatics analysis to researchers using mouse models. For more information, please see here or contact mmrrc@missouri.edu.